Table 1.

Input and Output Variables in the Breast Cancer Progression Model

1-month age-adjusted transition probabilities [20,21]	Age	PDCIS-L	PL-R		PR-D
	≤49	0.045	0.025		0.012
	50–54	0.036	0.020		0.010
	55–59	0.023	0.013		0.006
	60–69	0.020	0.011		0.005
	≥70	0.015	0.008		0.004
	All	0.028	0.016		0.007
		DCIS	Local	Regional	Distant
Mean age at diagnosisa [24]	Age	58.58	60.21	57.67	61.06
Life expectancyb[24]	40–49	13.94 yrs	12.85 yrs	10.02 yrs	3.46 yrs
	50–54	13.87 yrs	12.70 yrs	9.62 yrs	2.61 yrs
	55–59	13.19 yrs	12.19 yrs	9.31 yrs	2.69 yrs
	60–69	12.28 yrs	11.36 yrs	8.58 yrs	2.67 yrs
	≥70	9.26 yrs	8.35 yrs	6.21 yrs	1.80 yrs
	All	12.42 yrs	11.13 yrs	8.76 yrs	2.58 yrs
Lifetime breast cancer- attributable costs [22]		$67,598	$67,598	$86,516	$69,449
Total medical costs [23]		$127,596	$111,072	$101,063	$65,940
Stage shiftc		DCIS	Local	Regional	Distant
Initial distributiona at time 0		0.183	0.452	0.295	0.07
Distribution at time 3-months		0.168	0.445	0.310	0.076
Distribution at time 6-months		0.154	0.438	0.325	0.083
Distribution at time 9-months		0.142	0.430	0.339	0.090

Data Sources:

^a(SEER, 2000–2004, African-American and Latina women ≥ 40yrs);

^b(SEER, 1990–2004, African American and Latina women ≥ 40yrs);

^c(TreeAge Software, Inc. Williamstown, MA, USA).