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In-situ observation of (PLL/PLGA)3.5/CaCO3RhoB-PLGA/(PLL/PLGA)10.5 films. CLSM images (a1, b1) under fluorescence mode and (a2, b2) under transmittance mode. (c) SEM image of (PLL/PLGA)3.5/CapsuleRhoB-PLGA/(PLL/PLGA)10.5 film. (a1, a2) before and (b1, b2) after CaCO3 template removal. RhoB-PLGA served as a drug binding agent and was impregnated into CaCO3 particles.
