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Maze comparison in untreated male rats: Untreated rats tested in the Zero spent a larger percentage of time in the open (A) and exhibited more head dips (B) than rats in the Plus. Rats tested in the Plus had increased closed area entries (C) and start latencies (D) compared to rats tested in the Zero. **p ≤ 0.01; ***p ≤ 0.001. Zero N = 21; Plus N = 22.
