Table 1.

Clinical information and summary of clones generated from each time point with associated phenotype.

Samples	Age (years)	CD4 count	CD4 %	CD4:CD8 ratio	Viral Load	Biological Phenotype$	Clones V1-V4 env#	Full length env*
TM18A	5.0	1 239	20	0.31	699 740	R5	predicted CCR5, n=19	R5, n=10
TM18B	6.6	202	11	0.13	500 000	R5/R5X4	predicted CCR5, n=9 predicted CXCR4, n=13	R5, n=3 R5X4, n=3
TM18C	7.4	7	1	0.01	177 797	R5/R5X4	predicted CCR5, n=6 predicted CXCR4, n=21	R5, n=6 R5X4, n=3

^$Coreceptor usage previously described ⁶, ⁷, ²¹.

^#Coreceptor usage predicted with C-PSSM.

^*Phenotype determined using NP2.CD4 cell lines expressing either CCR5 or CXCR4.