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. 2010 Oct 13;36(2):434–444. doi: 10.1038/npp.2010.174

Figure 7.

Figure 7

Analysis of AcbC pERK immunoreactivity and D1 mRNA in animals expressing CPP. (a and b) Photomicrographs of striatal tissue sections labeled with D1 antisense (a) or sense (b) riboprobe. (c) COC-CPP expression in drug-unpaired (n=6) and drug-paired (n=12) animals, indicated as change in time spent in the COC-paired compartment from the initial to the final test (difference score). * One-way ANOVA, p<0.005. (d) Quantification of AcbC pERK+ cells and cells double-labeled for pERK and D1 in drug-paired animals. (e) Examples of AcbC cells double-labeled for pERK and D1 mRNA in COC-paired animals (solid arrows), as in contrast with cells single-labeled for D1 mRNA (open arrows). The criteria for identifying cells as D1/pERK double labeled were the same as indicated for the PPE/pERK cells (Figure 6 legend). Scale bars=100 μm; bar in panel (b) also applies to panel (a).