Figure 7).

The vascular response to prazosin was similar in both the high-fat diet rich in unsaturated fatty acids (U-HFD) group and the control (C) group. A Curves of contractile response to noradrenaline (Nor) in the presence or absence of prazosin (Pra) in an aorta from the control group. B Curves of contractile response to Nor in the presence or absence of Pra in aortas from the U-HFD group. C Both groups showed similar pharmacological behaviour to Nor in the presence of the alpha-1-antagonist Pra. Each point represents mean ± SEM, n=6. *P<0.01; **P<0.001; ^***P<0.0001 versus C curve