Table 2. Follow-up endpoints results in patients with CL treated with Sbvor miltefosine.
Follow-up endpoints | Sbv | Miltefosine | P value |
Nā=ā30 | Nā=ā60 | ||
End of Treatment | 20 days | 28 days | |
Apparent cure (%) | 1 (3.3) | 1 (1.7) | 0.61 |
Failure (%) | 29 (96.7) | 59 (98.3) | |
Lost in follow-up (%) | 0 | 0 | |
2 months after treatment | |||
Apparent cure (%) | 18 (60.0) | 49 (81.7) | 0.03 |
Failure (%) | 12 (40.0) | 11 (18.3) | |
Lost in follow-up (%) | 1 | 2 | |
6 months after treatment | |||
Definitive cure (%) | 16 (53.3) | 45 (75.0) | 0.04 |
Clinical Failure (%) | 14 (46.7) | 15 (25.0) | |
Lost in follow-up (%) | 1 | 2 | |
95% CI of cure rate | 35.5% to 71.2% | 64.0% to 86.0% | |
Difference in cure rate and 95% CI | 21.7% (0.08 to 42.7) |