Table 1. Epithelial tumors in organ homograft recipients.

Case No.	Transplant center	Age at time of transplant (years)	Sex	Donor	Immunosuppression by					Type of tumor	Time after transplantation (months)	Organs involved	Outcome	Referring physician
					Splenectomy	Thymectomy	Imuran	Prednisone	ALG
1	Denver	37	F	Unrelated living	Yes	Yes	Yes	Yes	No	Squamous cell carcinoma in situ	50	Cervix of uterus	Alive, no recurrence after hysterectomy
2	Minneapolis	28	F	Brother	No	No	Yes	Yes	No	Squamous cell carcinoma in situ	30	Cervix of uterus	Alive, no recurrence after hysterectomy	R. L. Simmons
3	Montreal	38	F	Cadaver	No	No	Yes	Yes	Yes	Squamous cell carcinoma in situ	6	Cervix of uterus	Alive, no recurrence after cryosurgery	K. Pritzker
4	Los Angeles	38	F	Mother	No	No	Yes	Yes	No	Squamous cell carcinoma in situ	35	Cervix of uterus; anterior wall of vagina	Alive, no recurrence after excision	A. Gordon
5	Richmond	33	F	Sister	No	No	Yes	Yes	No	Squamous cell carcinoma in situ	36	Cervix of uterus	Cone biopsy; patient being observed at regular intervals	H. Lee
6	Denver	26	F	Father	Yes	No	Yes	Yes	No	Squamous cell carcinoma in situ	65	Cervix of uterus	Died of causes unrelated to carcinoma
7	Denver	17	F	Father	Yes	No	Yes	Yes	Yes	Squamous cell carcinoma in situ	51	Cervix of uterus	Alive, awaiting hysterectomy
8	Minneapolis	32	F	Sister	Yes	No	Yes	Yes	No	Squamous cell carcinoma in situ	45	Cervix of uterus	Alive, no recurrence after hysterectomy	R. L. Simmons
9	Denver	40	M	Unrelated living	Yes	No	Yes	Yes	No	Superficial squamous cell carcinoma	66	Lower lip	Alive, no recurrence following excision
10	Denver	39	M	Brother	Yes	Yes	Yes	Yes	No	Superficial squamous cell carcinoma	36	Lower lip	Alive, no recurrence following excision
11	Louisville	35	M	Brother	No	No	Yes	Yes	No	Squamous cell carcinoma	8	Lower lip	Alive, no recurrence following excision	D. Leb
12	Los Angeles	27	M	Mother	No	No	Yes	Yes	No	Squamous cell carcinoma	25	Lower lip	Alive, no recurrence following excision	R. Goldman
13	Los Angeles	25	F	Brother	No	No	Yes	Yes	No	Squamous cell carcinoma	35	Lower lip	Alive, no recurrence following excision	R. Goldman
14	Salt Lake City	42	M	Cadaver	No	No	Yes	Yes	Yes	Squamous cell carcinoma	32	Lip	Alive, no recurrence following excision	L. Stevens
15	San Francisco	28	M	Cadaver Cadaver	Yes	No	Yes	Yes	No	Infiltrating squamous cell carcinoma	32	Lower left lip	Alive, recurrent lesion in lip removed 6 months after primary excision	F. O. Belzer
16	San Francisco	23	M	Brother	Yes	No	Yes	Yes	No	Infiltrating squamous cell carcinoma	37	Right lower lip	Alive, no recurrence following excision	F. O. Belzer
17	Denver	40	M	Unrelated living	Yes	Yes	Yes	Yes	No	Squamous cell carcinoma	32	Skin of ear	No recurrence after excision, died of other causes
18	Denver	43	M	Uncle	Yes	No	Yes	Yes	Yes	Basal cell carcinoma	33	Nasolabial fold	Alive, no recurrence following excision
19	Denver	30	M	Brother	Yes	Yes	Yes	Yes	No	Basal cell carcinoma	75	Nasolabial fold	Alive, no recurrence following excision
20	Denver	34	M	Sister	Yes	No	Yes	Yes	No	Squamous cell carcinoma	74	Left forearm; right forearm; right arm; scalp	Dead (myocardial infarction)
21	Stockholm	58	M	Cadaver	No	No	Yes	Yes	No	Multiple squamous cell carcinomas	38	Scalp	Alive	C. Franksson
22	Denver	22	M	Cousin	Yes	No	Yes	Yes	No	Squamous cell carcinoma	78	Left hand	Alive, no recurrence following excision
23	Denver	30	M	Brother	Yes	No	Yes	Yes	Yes	Superficial squamous cell carcinomas	36	Face (3 areas)	Alive, 4 fresh areas excised from face and neck 4 months after initial lesions
24a	Sydney	44	F	Cadaver	No	No	Yes	Yes	No	Basal cell carcinoma	3	Nose	Alive following radiotherapy	J. F. Mahony
25	Sydney	48	F	Cadaver	No	No	Yes	Yes	No	Multiple squamous cell carcinomas Basal cell carcinoma	29	Forehead; right nasolabial fold; left temple; left preauricular lymph node	Alive following excisions and radiotherapy	J. H. Stewart
26	Denver	21	M	Father	Yes	No	Yes	Yes	No	Squamous cell carcinoma	87	Skin of face	Alive following excision	W. Alexander
27	San Francisco	41	M	Brother	Yes	No	Yes	Yes	No	Squamous cell carcinoma	73	Multiple sites dorsum of left hand	Alive following wide excision	F. O. Belzer
28	San Francisco	46	M	Sister	Yes	No	Yes	Yes	No	Squamous cell carcinoma	76	Floor of mouth; tongue; cervical lymph nodes	Dead	F. O. Belzer
29	Nashville	34	M	Cadaver	No	No	Yes	Yes	No	Squamous cell carcinoma	62	Metastases in lymph nodes of neck; later widespread metastases; primary site of tumor unknown	Dead	C. Zukoski
30	Montreal	13	M	Brother	No	No	Yes	Yes	No	Hepatocellular carcinoma	32	Liver	Dead	K. Pritzker
31	Toronto	8	F	Cadaver	No	No	Yes	Yes	Yes	Well differentiated hepatoma	13	Liver	Dead	A. Millner
32	Minneapolis	27	M	Brother	Yes	No	Yes	Yes	No	Undifferentiated carcinoma	10	Liver; brain; bone marrow	Dead	C. Hitchcock
33	Nashville	47	M	Cadaver	No	No	Yes	Yes	No	Undifferentiated carcinoma	19	Lung; mediastinal lymph nodes; brain; liver	Dead	C. Zukoski
34	Denver	44	F	Sister	Yes	No	Yes	Yes	Yes	Moderately differentiated adenocarcinoma	31	Lung	Dead
35	San Francisco	46	M	Son; cadaver	Yes	No	Yes	Yes	No	Alveolar cell carcinoma of lung	9	Lungs	Dead	S. Kountz
36	Sydney	43	F	Cadaver	No	No	Yes	Yes	Yes (after development of tumor)	Adenocarcinoma	32	Lungs; mediastinal lymph nodes; liver	Dead	J. F. Mahony
37	Minneapolis	16	F	Cadaver	No	No	Yes	Yes	No	Dysgerminoma	32	Ovary; peritoneum; mediastinal and axillary lymph nodes	Dead	W. Kelly
38a	Louisville	32	M	Brother	Yes	No	Yes	Yes	No	Embryonal cell carcinoma	2	Testis; abdominal organs; ureter of transplanted kidney; lung	Dead	D. Leb
39	Ghent	53	F	Cadaver	No	No	Yes	Yes	No	Adenocarcinoma	35	Sigmoid colon; liver	Dead	F. Derom
40a	Chicago	41	M	Brother	No	No	Yes	Yes	No	Adenocarcinoma	1	Colon	Dead	D. Jonasson
41b	Cape Town	52	M	Cadaver	No	No	Yes	Yes	Yes	Anaplastic small cell adenocarcinoma	17	Stomach; liver; mesentery; peritoneum	Dead	S. Bosman
42c	Toronto	21	M	Cadaver	No	No	Yes	Yes	Yes	Highly anaplastic transitional cell tumor	6	Kidney; liver; brain; heart; lung	Dead	G. DeVeber
43a	Cleveland	45	M	Cadaver	No	No	Yes	Yes	Yes	Adenocarcinoma	1	Thyroid gland	Alive following thyroidectomy	S. Deodhar
44	San Francisco	32	F	Brother Cadaver	Yes	No	Yes	Yes	No	Adenocarcinoma	32	Breast; axillary lymph nodes	Alive following radical mastectomy	F. O. Belzer

^aTumors may have been present at time of transplantation.

^bHeart transplant recipient.

^cTumor may have been present in homograft at time of transplantation.