Table 2. Mesenchymal tumors in organ homograft recipients.

Case No.	Transplant center	Age at time of transplant (years)	Sex	Donor	Immunosuppression by					Type of tumor	Time after transplantation (months)	Organs involved	Outcome	Referring physician
					Splenectomy	Thymectomy	Imuran	Prednisone	ALG
1	Denver	14	M	Mother	Yes	No	Yes	Yes	Yes	Reticulum cell sarcoma	5½	Brain	Dead
2	Denver	23	M	Father	Yes	Yes	Yes	Yes	No	Reticulum cell sarcoma	30	Thyroid; liver; lung; stomach; prostate; pituitary; skin; psoas muscle	Dead
3	Edinburgh	26	F	Mother	No	No	Yes	Yes	Yes	Reticulum cell sarcoma	25	Lymph nodes; pleura; spleen; liver; ovary; adrenal; bone marrow; transplanted kidney	Dead	M. Woodruff
4	Cleveland	32	M	Cadaver	No	No	Yes	Yes	Yes	Reticulum cell sarcoma	22	Buttock; lungs; aortic lymph nodes	Dead	S. D. Deodhar
5	Richmond	38	M	Cadaver	No	No	Yes	Yes	No	Reticulum cell sarcoma	31	Lung; aortic lymph nodes	Dead	J. Pierce
6	Auckland	34	M	Cadaver Cadaver Cadaver	No	No	Yes	Yes	No	Reticulum cell sarcoma	7	Tongue; esophagus; liver	Dead	P. Doak
7	Auckland	46	F	Cadaver	No	No	Yes	Yes	No	Reticulum cell sarcoma	9	Brain	Dead	P. Doak
8	New York	18	M	Uncle	No	No	Yes	Yes	No	Reticulum cell sarcoma	9	Brain	Dead	R. Porro
9	New York	36	M	Cadaver	No	No	Yes	Yes	No	Reticulum cell sarcoma	10	Brain	Dead	F. Veith
10	Richmond	29	M	Brother	Yes	No	Yes	Yes	No	Reticulum cell sarcoma	67	Widespread lymph nodes; liver; vertebrae	Dead	H. Lee
11	Little Rock	21	M	Father	Yes	No	Yes	Yes	No	Reticulum cell sarcoma	24	Brain	Dead	C. Araoz
12	San Francisco	39	F	Sister	Yes	No	Yes	Yes	No	Reticulum cell sarcoma	14	Brain; lungs	Dead	F. O. Belzer
13	Richmond	18	M	Father	Yes	No	Yes	Yes	No	Reticulum cell sarcoma	73	Widespread lymph nodes; liver; pancreas; bone marrow; meninges; bladder; testes; transplanted kidney; accessory spleen; sciatic nerve; lung	Dead	H. M. Lee
14	Oklahoma City	19	F	Cadaver	No	No	Yes	Yes	No	Reticulum cell sarcoma	13	Lungs; liver; spleen; rectum; transplanted kidney; mesentery; bone marrow	Dead	Y. Muto
15	Chicago	52	M	Cadaver	No	No	Yes	Yes	No	Reticulum cell sarcoma	7½	Brain	Dead	N. Levine
16	New York	28	M	Cadaver	No	No	Yes	Yes	No	Reticulum cell sarcoma	7	Liver	Dead	L. Burrows
17	San Francisco	40	F	Cadaver Cadaver	No	No	Yes	Yes	No	Reticulum cell sarcoma	14	Brain	Dead	F. O. Belzer
18	Galveston	45	M	Cadaver	No	No	Yes	Yes	Yes	Reticulum cell sarcoma	19	S.c. tissues of buttock	Alivec	J. C. Fish
					(Had thoracic duct fistula)
19	Zurich	50	F	Cadaver	No	No	Yes	Yes	Yes	Malignant reticulosis	8	Liver; spleen; lymph nodes; bone marrow; esophagus; tongue; transplanted kidney; adrenal glands	Dead	W. Wegmann
					(Had thoracic duct fistula)
20	Israel	34	F	Cadaver	No	No	Yes	Yes	Yes	Reticulum cell sarcoma	9	Brain	Deadd	B. Myers
										Kaposi's sarcoma		Skin
21	Israel	27	M	Cadaver	No	No	Yes	Yes	Yes	Kaposi's sarcoma	8	Skin; mucosa of mouth	Alivee	B. Myers
22	New York	35	F	Cadaver	No	No	Yes	Yes	No	Visceral Kaposi's sarcoma	10	Lungs; esophagus; stomach; urinary bladder; mediastinal and abdominal lymph nodes	Dead	J. H. Siegel
23	Denver	20	F	Father	Yes	No	Yes	Yes	Yes	Unclassified lymphoma	7	Brain	Alive following radiotherapy
24	Los Angeles	23	M	Cadaver	No	No	Yes	Yes	No	Unclassified lymphoma	46	Brain	Dead	R. Goldman
25a	Montreal	29	M	Cadaver	No	No	Yes	Yes	Yes	Unclassified lymphoma	2	Spinal cord	Dead	P. Daloze
26	San Francisco	21	M	Brother Cadaver Cadaver Cadaver	Yes	No	Yes	Yes	No	Reticulum cell sarcoma	41	Brain (multifocal); cervical lymph nodes	Dead	F. O. Belzer
27a	Edmonton	8	M	Father	No	No	Yes	Yes	No	Lymphosarcoma	3½	Brain; meninges	Dead	W. Lakey
28	Boston	34	M	Cadaver; half-sister	No	No	Yes	Yes	No	Leiomyosarcoma	47	Stomach; perigastric lymph node; peritoneum; bowel; liver; lungs; vertebrae and ribs	Dead	R. E. Wilson
29	Montreal	36	M	Cadaver	No	No	Yes	Yes	No	Leiomyosarcoma	51	Small bowel; liver; pancreas	Dead	L. D. MacLean
30b	Chapel Hill	39	M	Cadaver	No	No	Yes	Yes	Yes	Synovial sarcoma	12	Lungs; liver; small bowel; right popliteal fossa	Dead	W. B. Blythe
31	New York	40	F	Cadaver	No	No	Yes	Yes	No	Rhabdomyosarcoma	19	Iliac muscles	Dead	L. Burrows

^aTumors may have been present at time of transplantation.

^bTumor first diagnosed 9 months after immunosuppressive therapy had been discontinued.

^cAlive 3 months following radical local excision and radiotherapy and reduction of immunosuppressive therapy.

^dTumors had disappeared following resection or irradiation of the lesions and withdrawal of ALG and Imuran therapy; no tumors at autopsy.

^eNo recurrence after irradiation of lesions and withdrawal of ALG and Imuran therapy.