TABLE 1.

Biochemistry of liver tissues at the end of preservation and at 1 hr after reperfusion

Groups	ECa	TAN (nmol/g liver)	ATP (nmol/g liver)	ADP (nmol/g liver)	AMP (nmol/g liver)	TPC (nmol/g liver)	HX (nmol/g liver)	MDA (nmol/mg protein)	MPO (U/min/mg protein)
Normal	1.13±0.02	3798.7±206.3	2578.08±116.40	861.74±126.14	358.83±29.65	128.3±53.9	73.35±38.77	0.72±0.13	0.54±0.31
At end of 48-hr preservation
Laz(0)	0.44±0.07b	2919.7±225.3b	182.52±54.75b	539.50±64.46b	2197.69±285.04b	3042.3±223.2b	1845.75±270.98b	1.23±0.39b	0.00±0.00b
Laz(6)	0.42±0.11b	3332.6±488.4b	207.74±117.50b	607.16±177.92b	2517.72±405.37b	2914.5±250.0b	1871.04±243.78b	1.07±0.27b	0.00±0.01b
Laz(10)	0.44±0.12b	3392.4±343.6b,c	229.42±124.58b	626.06±107.45b	2536.95±482.33b	2919.3±180.4b	1928.24±196.39b	1.15±0.39b	0.13±0.16b
Laz(15)	0.38±0.11b	3258.8±317.4b	165.11±95.96b	549.41±174.25b	2544.31±263.21b	2724.9±81.4b,c	1854.67±265.12b	1.18±0.23b	0.00±0.00b
At 1 hr after reperfusion
Laz(0)	1.06±0.03b	2179.5±683.4b	1300.7±492.0b	516.26±194.98b	362.51±91.37	168.14±87.44	114.04±81.97	0.33±0.04b	4.30±1.73b
Laz(6)	10.8±0.02b	2373.0±540.0b	1469.4±332.5b	546.54±153.25b	357.09±73.76	102.01±29.22	55.77±13.60	0.35±0.04b	3.41±1.78b
Laz(10)	1.11±0.05	2501.5±599.3b	1483.1±340.0b	649.63±248.72	368.81±81.57	163.53±119.96	101.60±109.55	0.37±0.09b	2.90±2.28b
Laz(15)	1.04±0.09b	2122.7±223.3b	1118.9±368.6b	545.12±98.75b	458.64±164.31	412.67±697.64	307.80±573.24	0.49±0.28b	2.85±2.37b

^aEC: Energy charge; TAN: total adenine nucleotides; ATP: adenine triphosphate; ADP: adenine diphosphate; AMP: adenine monophosphate; TPC: total purine catabolites; HX: hypoxanthine; MDA: malondialdehyde; MDO: myeloperoxidase.

^bP<0.05 versus normal value.

^cP<0.05 versus Laz(0) group.