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. 2010 Sep 17;299(6):H1891–H1901. doi: 10.1152/ajpheart.00655.2010

Table 2.

TMS inhibits cardiac hypertrophy associated with DOCA-salt-induced hypertension in rats

UNX DOCA-Salt UNX + TMS DOCA-Salt + TMS
BW, g 494.0 ± 15.1 375.0 ± 15.9* 496.4 ± 14.7 455.8 ± 16.1
HW, mg 1,484.0 ± 24.6 2,032.0 ± 81.3* 1,426.0 ± 29.8 1,687.0 ± 27.0
HW/BW, mg/g 3.0 ± 0.1 4.4 ± 0.2* 2.9 ± 0.2 3.6 ± 0.2
BNP:β-tubulin mRNA, ΔΔCt 1.0 6.5 ± 1.0* 0.6 ± 0.1 1.4 ± 0.2

Data are means ± SE (n = 5). BNP data are displayed following normalization to uninephrectomized (UNX) control rat values. DOCA, deoxycorticosterone acetate; TMS, 2,3′,4,5′-tetramethoxystilbene; BW, body weight; HW, heart weight.

*

P < 0.05, UNX vs. DOCA-salt.

P < 0.05, DOCA-salt vs. DOCA-salt + TMS.