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A: effect of early and delayed Psora-4 treatments on urinary protein excretion. *P < 0.05 vs. vehicle group. B: body weight. C: kidney weight. D: creatinine clearance (Ccr). Each plot shows the means ± SD for 6 rats. Closed circles, vehicle group. Open circles, early Psora-4 group (from day 0 to day 21). Double circles, delayed Psora-4 group (from day 7 to day 21). *P < 0.05 vs. vehicle group.
