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Effect of intracellular acidification on MA/MA+-induced changes in H2O-injected oocytes. Exposing control oocytes to 5 mM MA/MA+ did not induce any significant changes in pHi or Vm at steady-state pHi (segment ab) or when pHi was lowered by 20 mM butyrate (segment de). Tracing shows that butyrate caused substantial decrease in pHi (segment cd) and small depolarization of the cell. All changes were reversible.
