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. 2010 Dec 3;8:107. doi: 10.1186/1477-7819-8-107

Figure 1.

Figure 1

Histopathology-Lung Biopsy:Haematoxylin and Eosin stained slides [1A,1B and 1C]; Immunohistochemical stained slides [1D, 1E and 1F]. 1A, 1B, 1C: Hemotoxylin-eosin stain slides at medium power (magnification ×250) demonstrates the neoplastic cells in a perivascular peribronchial lymphatics (1A, black arrow head), along the septal vessels (1B, black arrow head), and subpleural lymphatics (1C, black arrow). 1D, 1E, 1F: Immunohistochemicals stain at medium power (magnification ×250): p16 shows strong positive nuclear and cytoplasmic staining of the peribronchial lymphatics (1D, black arrow head); high molecular weight keratin shows strong positive membranous staining of the lesional cells (1E, black arrow); cytokerain 7 (CK7) demonstrates the strong positive staining of the lesional cells in the subpleural lymphatics (1F, black arrow).