Fig. 3.

Timed accumulation curves of fluorescein (FL) tracer in the growth plate and metaphyseal vasculature. A: exercise significantly increased FL arrival and entry into the growth plate. Within 5 min after tracer injection, absolute FL concentrations were ∼1.5-fold greater in the growth plates of the wheel-running than nonrunning groups, independent of temperature. B: there was also more tracer in the adjacent metaphyseal vasculature of the wheel-running groups: >1.3 times more FL had accumulated in the metaphyseal region of the runners by 5 min (temperatures pooled), indicating enhanced tracer delivery into and around the growth plates of exercised mice. These differences in absolute values, however, were not statistically significant because of within-group variation. Group means are shown without error bars to facilitate viewing.