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. 2010 Aug 26;109(6):1592–1599. doi: 10.1152/japplphysiol.00736.2010

Table 2.

Morphometric data from microscopic studies from various literature sources obtained by stereological analysis of mouse lungs using animals of different strain, age, and size

Source Strain Age, wk Mb, g VL, cm3 Lm, μm NV(a), 103 mm−3 h, μm v(a), 103 μm3 Sa/Va, cm−1
Voswinckel (32) C57BL/6 12–16 24.3 0.721 54 37 51 740
Knudsen (14) C57BL/6 12 0.680 35 14.1 39 59 1150
Soutière (29) C57BL/6J 6–8 0.95–1.45 45–63
Fehrenbach (6) C57BL/6 12–14 0.432 2.7
Mitzner (20) C57BL/6 10–12 1.2 52 770
Knust (16) C57BL/6 6.5–10 20.6 0.307 85 9.6 39 59 470
Lee (17) C57BL/6J 7–9 38
Kang (13) C57BL/6J 12 1.7 55
Knudsen (15) C57BL/6* 12 0.64 39 915
Overall range 6–16 20–25 0.4–1.5 40–80 3–14 3050 500–1000
This study C57BL/6N 12–16 21–27 ∼1.2 61.7 ± 12 3.2 ± 1.3 55 ± 8 670 ± 133

The measured lung volumes varied by a factor of 3, some of which may be due to different inflation levels achieved in fixation.

*

SPD-deficient mice treated with recombinant SPD;

h = v(alv)1/3.