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. 2010 Dec 13;4:152. doi: 10.3389/fncom.2010.00152

Table 3.

List of LTD models.

Model Methods Cell type Phases Time Outputs Size
Achard and De Schutter (2008) Det. Reac. Elect./GENESIS/Kinetikita Cerebellar PC Ind. LTD 1 s Ca2+ L
Brown et al. (2008) Det. Reac. Diff./Virtual Cellb Cerebellar PC LTD 0.4–2 s IP3 M
Doi et al. (2005) Det. Reac./GENESIS/Kinetikita Cerebellar PC Ind. LTD 0.2–1 s Ca2+ L
Fiala et al. (1996) Det. Reac. Elect. Cerebellar PC Ind. LTD gKCa M
Hellgren Kotaleski and Blackwell (2002) Det. Reac. Diff./XPPc Cerebellar PC LTD 1–5 s Ca2+ S
Hellgren Kotaleski et al. (2002) Det. Reac. Diff./XPPc Cerebellar PC Ind. LTD 5–30 s PKC M
Hernjak et al. (2005) Det. Reac. Diff./Virtual Cellb Cerebellar PC Ind. LTD 0.1–4 s Ca2+ M
Holthoff et al. (2002) Det. Reac. Diff. Elect./MATLAB® Neocortical layer V PN Ind. LTD 0.5 s Ca2+ S
Kuroda et al. (2001) Det. Reac./GENESIS/Kinetikita Cerebellar PC Ind. STD/E-,L-LTD 15–100 min AMPAR L
Murzina (2004) Det. Reac. Diff. Elect. Cerebellar PC Ind. LTD Kinase, receptor M
Ogasawara et al. (2007) Det. Reac. Diff. Elect. Cerebellar PC Ind./Expr./Maint. LTD 20–60 min AMPAR L
Ogasawara and Kawato (2009) Det. Stoch. Reac. Cerebellar PC Ind./Maint. LTD 10 s to 70 min Kinase S
Schmidt et al. (2007) Det. Reac. Diff./Mathematica, FEMLAB Cerebellar PC Ind. LTD 0.2–4 s Ca2+, CaM L
Schmidt and Eilers (2009) Det. Reac. Diff./Mathematica Cerebellar PC Ind. LTD 0.04–3 s Ca2+, CaM S
Steuber and Willshaw (2004) Det. Reac. Elect. Cerebellar PC Ind. LTD gKCa S
Tanaka et al. (2007) Det. Reac. Cerebellar PC Ind. LTD AMPAR M
Yang et al. (2001) Det. Reac. Elect./GENESIS/Chemesisd Cerebellar PC Ind. LTD 10–100 s PKC L

Models are in alphabetical order by the first author and according to the publication month and year. Tabulated characteristics are the method and model types (Det., Stoch., Reac., Diff., Elect., and simulation environment), cell type, phases of LTD, time required for the dynamics of the model to reach a steady state, model outputs, and size of the model based on the number of different chemical species or other model variables (S, M, L). All abbreviations are given in the list of abbreviations.

bVirtual Cell (http://vcell.org; Schaff et al., 1997; Slepchenko et al., 2003).

dGENESIS/Chemesis (http://www.genesis-sim.org/GENESIS/; http://krasnow.gmu.edu/CENlab/software.html; Bower and Beeman, 1998; Blackwell and Hellgren Kotaleski, 2002).