Increased fluctuations in phase difference associated with the end of a seizure, in patient 3, with temporal lobe epilepsy. The upper plot shows the phase locking value between two electrodes located in the right hippocampus, and the lower graph represents the fluctuations in phase difference, evaluated at 20 ± 2 Hz. The seizure is marked by a horizontal line (‘ictus’). Note, in this case, the decrease in synchrony (R) associated with the growth of fluctuations at the end of the ictal event