. Author manuscript; available in PMC: 2012 Jan 1.

Published in final edited form as: Gastroenterology. 2010 Oct 13;140(1):210–220.e4. doi: 10.1053/j.gastro.2010.09.048

Table 1.

Categorical description of gastric lesions observed in H. pylori-monoassociated and GF control INS-GAS mice at 5, 7, 9, and 11 mpi.

mpi	M/F	H. pylori	N	Pathology Subfeatures, median (range)
mpi	M/F	H. pylori	N	I	ED	A	H	PM	D
5	C	−	11	0.5 (0–1)	0.5 (0–1)	0 (0-0)	0 (0–0.5)	0 (0-0)	0 (0-0)
	M	+	5	2 (1–2.5)^**	2 (1–2)^*	1.5 (1.5–2)^*	1.5 (0–2)^**	1.5 (1.5–2.5)^**	1 (0–1.5)^*
	F	+	6	1.5 (1–2)^*	1.5 (1–2)^*	1 (0.5–1.5)^*	0.75 (0.5–1)^**	0.5 (0–0.5)^*	0.5 (0–0.5)^*
7	C	−	11	0.5 (0–1)	0.5 (0–1)	0 (0-0)	0 (0–0.5)	0 (0-0)	0 (0-0)
	M	+	5	2.5 (2–2.5)^*	2.5 (2.5–3)^*	2.5 (2–3)^*	3.5 (3–4)^*	2.5 (2–3)^*	2.5 (2–3)^*
	F	+	7	2 (2–3)^*	2.5 (2–3)^*	2 (1.5–2)^*	2.5 (2–3.5)^*	1.5 (1.5–2)^*	1.5 (1.5–2)^*
9	C	−	10	0.75 (0.5–1)	1 (0.5–1.5)	0.5 (0–1)	1.25 (1–2)	0.5 (0–1)	0.25 (0–0.5)
	M	+	4	2.5 (2–3)^**	3.25 (3–3.5)^*	3 (2–3.5)^**	3.25 (3–4)^**	3 (2–3)^*	3.25 (3–3.5)^**
	F	+	6	2.5 (2–2.5)^*	2.75 (2–3.5)^*	2.75 (1.5–3)^*	3 (2–3.5)^*	2.5 (2–3)^*	2.5 (2–3)^*
11	C	−	11	0.5 (0–1)	0.5 (0–1)	0.5 (0–1)	1 (0.5–2)	0.5 (0–1)	0.5 (0–1.5)
	M	+	4	2.75 (2–3)^**	3 (2.5–3.5)^*	3.25 (2–3.5)^**	3.5 (2.5–4)^**	3 (2–3.5)^*	3.5 (2–4)^**
	F	+	7	2.5 (2–3)^*	2.5 (2.5–3)^*	2.5 (2–4)^*	2.5 (2.5–4)^*	2.5 (2–3)^*	2.5 (1.5–3)^*

Abbreviations: mpi: months post infection, M. males, F. females, C. combined male and female, I. inflammation, ED. Epithelial defects, A. oxyntic atrophy, H. foveolar hyperplasia, PM. pseudopyloric metaplasia, D. dysplasia.

p<0.01

^**

p<0.05

Control male and female data were combined.