Table 2.
Maximum likelihood estimates of the means and variances of the log-abundances in Ep (TCR-restricted) and Wt (wild-type) mice repertoires along with bias-corrected, two-sided 95% confidence bounds generated via parametric bootstrap. In each population the regulatory (TR) and naive (TN) T-cells from (1) lymph nodes and (2) thymus are considered.
Ep | Wt | |||||||
---|---|---|---|---|---|---|---|---|
TN1 | TR1 | TN2 | TR2 | TN1 | TR1 | TN2 | TR2 | |
μ̂ | −4.54 | −3.90 | −3.58 | −3.80 | −3.70 | −2.97 | −3.55 | −2.90 |
95% Lo | −5.37 | −4.81 | −4.59 | −4.71 | −4.86 | −3.77 | −4.46 | −3.81 |
95% Up | −3.31 | −2.43 | −2.40 | −2.54 | −2.59 | −2.13 | −2.38 | −1.87 |
| ||||||||
σ̂ 2 | 2.03 | 1.93 | 1.66 | 1.70 | 1.99 | 1.48 | 1.84 | 1.31 |
95% Lo | 1.60 | 1.52 | 1.17 | 1.21 | 1.61 | 1.15 | 1.46 | 0.90 |
95% Up | 2.36 | 2.29 | 1.99 | 2.02 | 2.47 | 1.74 | 2.15 | 1.70 |