Fig. 1.

Severe heatstroke triggers the release of Hsp-72 into the circulation. a Effect of heat stress on Hsp-72 release into the circulation of sham control (n = 1), moderate (n = 1), and severe (n = 1) heatstroke baboons. Values represent plasma Hsp-72 concentration as a function of the core temperature. Error bars reflect duplicate measurements. Arrows indicate the onset of heatstroke that occurred at 42.5°C (moderate heatstroke) and 43.5°C (severe heatstroke). b Kinetics of Hsp-72 release in baboons (n = 6) subjected to severe heatstroke. Values represent mean ± SE. P values indicate the degree of significance in circulating Hsp-72 levels, when post-heat stress levels are compared with baseline (BL), using Student’s t test