Table 3.
Correlation of the number of multiplex reverse transcription polymerase chain reaction positive detections in each blood sample with disease stage in colorectal cancer patients n (%)
CRC patients (n = 88) |
No. of positive marker detections in each blood sample |
|||
0 | 1 | 2 | 3 | |
Stage A (n = 4) | 1 (25) | 2 (50) | 1 (25) | 0 (0) |
Stage B (n = 26) | 3 (11.5) | 5 (19.2) | 16 (61.5) | 2 (7.7) |
B1 (n = 9) | 1 (11.1) | 1 (11.1) | 7 (77.7) | 0 (0) |
B2 (n = 17) | 2 (11.8) | 4 (23.5) | 9 (52.9) | 2 (11.8) |
Stage C (n = 27) | 0 (0) | 6 (22.2) | 17 (63) | 4 (14.8) |
C1 (n = 5) | 0 (0) | 1 (20) | 3 (60) | 1 (20) |
C2 (n = 22) | 0 (0) | 5 (22.7) | 14 (63.6) | 3 (13.6) |
Stage D (n = 31) | 0 (0) | 2 (6.5) | 18 (58.1) | 11 (35.5) |
Disease staging according to the modified Astler-Coller classification. A positive correlation was revealed using Spearman’s test (Spearman’s ρ = 0.396, P < 0.001). CRC: Colorectal cancer.