Fig. 6.

Hypoxic pulmonary hypertension (PH) in wild-type and Id1-deficient mice. A: representative immunoblot for ID1 using rabbit monoclonal antibody clone 195–14 and β-actin in normoxic and 1-wk and 3-wk hypoxic wild-type (WT), Id1^+/−, and Id1 null lung lysates. B: right ventricular systolic pressures (RVSP) in wild-type, Id1^+/−, and Id1 null mice exposed to normoxia or 1-wk or 3-wk hypoxia. Each dot represents the mean RVSP from a single animal; bars indicate mean values for each group. Mouse numbers are indicated (n). ^aP < 0.05 vs. corresponding genotype normoxic control by one-way ANOVA with Bonferroni correction.