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. 2010 Sep 15;299(6):R1592–R1601. doi: 10.1152/ajpregu.00247.2010

Fig. 3.

Fig. 3.

Effects of glucocorticoid inhibition on muscle mass (A) C/EBP-δ (B) and MSTN (C) mRNA levels in TA muscle. A: effects of RU486 treatment with and without food deprivation on TA muscle mass. RU486 significantly attenuated the decrease in TA muscle mass with food deprivation. B: effects of RU486 treatment with and without food deprivation on C/EBP-δ mRNA levels in the TA muscle. RU486 treatment had no effect on C/EBP-δ mRNA levels in the Fed TA muscle but significantly attenuated the increase in C/EBP-δ mRNA levels with food deprivation. C: effects of RU486 treatment with and without food deprivation on MSTN mRNA levels in the TA muscle. RU486 treatment had no effect on MSTN mRNA levels in the Fed TA muscle but abolished the increase in MSTN mRNA levels with food deprivation. Bars represent means ± SE for 4 animals/group. *Significantly different from Fed vehicle (Veh)-injected mice, P < 0.05. †Significantly different from FD vehicle injected, P < 0.05. ‡Significantly different from Fed RU486-injected, P < 0.05.