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. 2003 Dec;133(4):1732–1746. doi: 10.1104/pp.103.028530

Figure 2.

Figure 2.

Multiple sequence alignment of the predicted extracellular region of the WAKL proteins. Amino acids that are identical among the WAKLs are shaded. Amino acids that are identical among the WAKs and WAKLs are indicated by the black dots. The predicted N-terminal signal sequences are underlined. The five variable domains analyzed for nonsynonymous to synonymous substitution ratios are underlined and indicated by roman numerals (I–V). The EGF2-like domain (EGF2) and calcium-binding EGF-like domain (EGF-Ca2+) are underlined. The amino acid substitutions in the EGF2-like domain are indicated by the asterisk. The cross indicates the amino acid substitutions in the EGF-Ca2+-like domain. The additional amino acid inserted before the last conserved Cys in the WAKL1 calcium-binding EGF-like domain is indicated with a diamond.