Tab. 2.
Physico-chemical properties of the prepared Gatifloxacin mucoadhesive systems
| Batch Code | Drug content uniformity (% ± S. D.) | Gelling capacity in STF | pH |
|---|---|---|---|
| Control | 99.58 ± 1.05 | − | 5.1 |
| GS1 | 99.58 ± 0.25 | + | 5.3 |
| GS2 | 98.91 ± 0.71 | ++ | 5.2 |
| GS3 | 99.32 ± 0.95 | +++ | 5.3 |
| GS4 | 98.73 ± 1.03 | +++ | 5.3 |
| GS5 | 99.51 ± 0.67 | +++ | 5.2 |
| GS6 | 99.45 ± 0.54 | +++ | 5.3 |
| GS7 | 98.64 ± 0.62 | +++ | 5.4 |
| GS8 | 100.20 ± 0.55 | +++ | 5.3 |
+…Gels after few minutes; ++…Gels immediately but remains for a few hours (less stiffer); +++…Gelation immediate and remains for extended periods and formed gels are stiffer.