Figure 3.
Gallery of antigen-independent contacts formed by activated human peripheral blood CD8+ T cells. Anti-CD3/CD28–stimulated peripheral blood CD8+ and CD4+ T cell contacts on Cy3–ICAM-1–GPI in the bilayer (the highest ICAM-1 density is white). The patterns were categorized based on the presence and completeness of pSMAC morphology. Only ring junction examples are provided for CD4+ T cells. The percentage of cells in each category is along the right margin. Results are representative of three experiments. Scale bar: 5 μm.