Table 2.
Endpointi | PI/NNRTI Comparison No. of Patients with Endpoint (Rate per 100 person years) |
NRTI Comparison No. Of Patients with Endpoint (Rate per 100 person years) |
||||||
---|---|---|---|---|---|---|---|---|
EFV (N=888) | LPV/r (N=883) | HR (95% CI) | P-value | ZDV+ddI (N=884) | d4T+3T C (N=887) | HR (95% CI) | P-value | |
AIDS or death | 163 (9.1) | 157 (8.7) | 1.04 (0.84–1.30) | 0.71 | 170 (9.6) | 150 (8.2) | 1.15 (0.93–1.44) | 0.20 |
Death | 106 (5.6) | 102 (5.4) | 1.05 (0.80–1.37) | 0.75 | 111 (5.9) | 97 (5.1) | 1.15 (0.88–1.51) | 0.31 |
AIDS | 80 (4.4) | 69 (3.7) | 1.18 (0.85–1.62) | 0.32 | 83 (4.6) | 66 (3.5) | 1.29 (0.94–1.79) | 0.12 |
Grade 4 event | 137 (7.9) | 129 (7.2) | 1.07 (0.84–1.36) | 0.57 | 142 (8.1) | 124 (7.0) | 1.16 (0.91–1.48) | 0.23 |