TABLE 2.
Survival and RVFV SN antibody titers of mice vaccinated three times with rKS1/RVFV and then challenged with RVFVa
| Route of vaccination | No. of surviving mice/no. of challenged mice (%) | RVFV SN titerb |
||
|---|---|---|---|---|
| Prevaccination | 14 days after 3rd vaccination | 17 days after RVFV challenge | ||
| Intraperitoneal | 10/10 (100) | <4 | 8 | 16 |
| Intramuscular | 9/10 (90) | <4 | 4 | 32 |
a
Mice were challenged subcutaneously with 100 LD50 of virulent RVFV 21 days after the third vaccination.
b
SN titers are the reciprocal of the last positive dilution determined with pooled sera from each group of mice.