TABLE 3.
Body temperatures and RVFV titers of vaccinated sheep challenged with RVFV
| Sheep (sex) | Group (inoculum) | Body temp (°C) (RVFV titer [log10 TCID50/ml]) at day post-RVFV challengea: |
||||
|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | ||
| 2517 (F) | 1 (rKS1/RVFV) | 39.0 | 39.8 (Neg) | 39.1 (Neg) | 38.8 (Neg) | 39.0 (Neg) |
| 2518 (M) | 1 (rKS1/RVFV) | 39.2 | 39.7 (Neg) | 39.1 (Neg) | 39.3 (Neg) | 39.2 (Neg) |
| 2519 (F) | 1 (rKS1/RVFV) | 39.3 | 39.5 (Neg) | 39.5 (Neg) | 39.6 (Neg) | 40.1 (Neg) |
| 3244 (M) | 1 (rKS1/RVFV) | 39.3 | 40.0 (Neg) | 38.7 (Neg) | 38.8 (Neg) | 39.0 (Neg) |
| 3248 (F) | 1 (rKS1/RVFV) | 39.1 | 40.6 (Neg) | 39.4 (Neg) | 39.0 (Neg) | 39.6 (Neg) |
| 2523 (M) | 2 (rKS1/gpt) | 39.0 | 41.4 (101) | 39.8 (101) | 39.4 (Neg) | 40.0 (Neg) |
| 3264 (F) | 2 (rKS1/gpt) | 39.1 | 40.5 (101) | 39.5 (101) | 39.0 (Neg) | 39.6 (Neg) |
| 3266 (F) | 2 (rKS1/gpt) | 39.0 | 41.0 (101) | 39.7 (101) | 39.3 (Neg) | 40.3 (Neg) |
| 3267 (M) | 2 (rKS1/gpt) | 39.4 | 40.3 (Neg) | 39.5 (Neg) | 39.0 (Neg) | 39.0 (Neg) |
| 3269 (M) | 2 (rKS1/gpt) | 39.2 | 41.0 (Neg) | 40.2 (Neg) | 39.3 (Neg) | 39.5 (Neg) |
| 2520 (M) | 3 (rKS1/RVFV) | 39.1 | 40.0 (Neg) | 39.5 (Neg) | 39.2 (Neg) | 39.6 (Neg) |
| 2521 (M) | 3 (rKS1/RVFV) | 38.7 | 39.3 (Neg) | 40.0 (Neg) | 37.2 (Neg) | ND (Neg) |
| 3252 (M) | 3 (rKS1/RVFV) | 39.0 | 40.1 (Neg) | 40.2 (Neg) | 39.9 (Neg) | 39.3 (Neg) |
| 3255 (M) | 3 (rKS1/RVFV) | 39.0 | 38.8 (Neg) | 39.6 (Neg) | 40.3 (Neg) | 40.1 (Neg) |
| 2524 (F) | 4 (saline) | 38.5 | 39.0 (Neg) | 39.5 (Neg) | 39.0 (Neg) | 38.9 (Neg) |
| 3271 (M) | 4 (saline) | 39.2 | 40.2 (Neg) | 39.3 (Neg) | 39.9 (Neg) | 40.5 (Neg) |
| 3273 (M) | 4 (saline) | 39.3 | 41.0 (102) | 39.7 (102) | 40.3 (102) | 40.0 (Neg) |
| 3274 (F) | 4 (saline) | 39.4 | 40.3 (102) | 41.6 (104) | 41.7 (101) | 39.7 (Neg) |
| 3246 (M) | 5 (rKS1/RVFV) | 39.2 | 40.0 (Neg) | 39.0 (Neg) | 38.8 (Neg) | 39.0 (Neg) |
| 3263 (F) | 5 (rKS1/RVFV) | 39.6 | 40.7 (Neg) | 40.2 (Neg) | 39.3 (Neg) | 39.0 (Neg) |
a
RVFV titers (in parentheses) are log10 TCID50/ml, and Neg indicates a virus titer of less than 101 TCID50/ml. Temperatures in boldface type are ≥40.3°C, which was the threshold for fever determined as 1.2°C (5 standard deviations) above the mean of 39.1°C for the 20 sheep at time zero in this table. ND indicates not done.