TABLE 1.
Demographics and clinical characteristics of the study subjects
| Characteristic | Value |
|---|---|
| No. of subjects | 105 |
| No. (%) of male subjects | 101 (96) |
| Mean age (yr) ± SD (range) | 67 ± 9 (50-82) |
| No. (%) of subjects 50-64 yr of age | 37 (35) |
| No. (%) of subjects ≥65 yr of age | 68 (65) |
| No. (%) of white subjects | 97 (92) |
| No. (%) of current tobacco smokers | 37 (35) |
| Mean FEV1/FVC ratio ± SDa | 0.52 ± 0.13 |
| Mean % predicted FEV1 ± SDa | 41.5 ± 15 |
| No. (%) of subjects with history of diseases other than COPD | |
| One or more diseases | 95 (90) |
| Heart disease | 37 (35) |
| Diabetes mellitus | 17 (16) |
a
Spirometric criteria for COPD were an FEV1 that was 80% or less of the predicted value and an FEV1/FVC ratio of less than 0.70, as described previously (18), where FEV1 is the forced expiratory volume in 1 s and FVC is the forced vital capacity.