TABLE 3.
Passive immunization of mice against challenge with various serovar strains of E. rhusiopathiae
| Immunizationa | Challenge strain (serovar, Spa protein expressed)b |
|||||
|---|---|---|---|---|---|---|
| 715 (18, SpaC) |
2017 (19, SpaB) |
Fujisawa (1a, SpaA) |
||||
| No. alive/ total no. | P | No. alive/ total no. | P | No. alive/ total no. | P | |
| rSpaC664 | 10/10 | 0.0000 | 10/10 | 0.0000 | 9/10 | 0.0001 |
| rSpaC427 | 10/10 | 0.0000 | 10/10 | 0.0000 | 9/10 | 0.0001 |
| rSpaC253 | 1/10 | 0.3049 | 1/10 | 0.3049 | 0/10 | 1.0000 |
| Control | 0/10 | 0/10 | 0/10 | |||
a
At 4 h after i.p. injection of 0.2 ml of serum, mice were challenged s.c. with strains of E. rhusiopathiae.
b
Data are presented as the number of mice alive/the total number of animals tested. The survival of mice was monitored for 14 days after challenge with strains of E. rhusiopathiae. P values are based on a comparison of alive/dead ratios for immunized mice with those for control mice, as calculated by the Fisher exact test.