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Three-dimensional microstructural parameters calculated using 2-dimensional data obtained from micro-CT of femoral bones from 4.5-month-old Fgf2+/+ and Fgf2–/– mice. Calculated morphometric indices included bone volume density (bone volume [BV]/trabecular volume [TV]), trabecular number [Tb.N = (BV/TV)/Tb.Th], and trabecular separation [Tb.Sp = (1/Tb.N)–Tb.Th]. ASignificantly different from Fgf2+/+ group; P < 0.05, Tukey-Kramer multiple comparison test (ANOVA).
