. Author manuscript; available in PMC: 2011 Sep 1.

Published in final edited form as: Eur J Pharmacol. 2010 Jun 8;641(2-3):128–134. doi: 10.1016/j.ejphar.2010.05.033

Table I.

HPLC of H-Preg and H-Prog in Brain and Serum after Intranasal or Intravenous Administration. Means are given with their S.E.M. and units are % of total recovered dpm eluting as intact neurosteroid.

	H-Pregnenolone
	10 min	60 min
Intranasal - Brain	35 ± 2.6	45 ± 18
Intranasal - Serum	3.7 ± 0.60	7.0 ± 0.54
Intravenous - Brain	26.0 ± 1.9	10 ± 1.2
Intravenous - Serum	26 ± 6.6	10 ± 3.7
	H-Progesterone
	10 min	60 min
Intranasal - Brain	9.5 ± 0.9	20 ± 2.6
Intranasal - Serum	13 ± 2.5	18.2 ± 0
Intravenous - Brain	7.9 ± 1.1	9.8 ± 2.0
Intravenous - Serum	13 ± 0.33	7.3 ± 0.75

10 min and 60 min values are means ± S.E.M., n = 2