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. Author manuscript; available in PMC: 2011 Dec 15.
Published in final edited form as: J Immunol. 2010 Nov 12;185(12):7480–7486. doi: 10.4049/jimmunol.1002771

FIGURE 6.

FIGURE 6

NKG2D blockade delays adenoviral clearance in vivo. RAG-2−/− mice were treated with 100 μg of anti-NKG2D mAb (Anti-NKG2D) or the control rat IgG (Rat IgG) 24 h and 6 h before intravenous injection of Ad-lacZ. 5 days after infection, liver tissues were harvested for analyses. (A) Cryosections were stained for LacZ expression by X-gal histochemistry. (B) Liver tissues were assayed for β-galactosidase (β-gal) activity. Data represent β-gal units ± SD per gram of liver protein. (C) Total genomic DNA were extracted and analyzed for adenoviral genome copies by quantitative real-time PCR. Data are representative of two independent experiments.