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. Author manuscript; available in PMC: 2011 Dec 15.
Published in final edited form as: J Immunol. 2010 Nov 12;185(12):7480–7486. doi: 10.4049/jimmunol.1002771

FIGURE 7.

FIGURE 7

NKG2D is critical for NK cell-mediated cytolysis on adenovirus-infected targets. C57BL/6 mice were injected intravenously with 2×109 pfu Ad-LacZ or left uninfected as the control. 24 h after infection, splenic NK cells were enriched from Ad-lacZ infected (Activated NK) or naïve (Naïve NK) mice, and assayed for NK cell lytic activity on Ad-lacZ infected macrophages in the presence of anti-NKG2D mAb (+Anti-NKG2D) or the rat IgG control (+Rat IgG) for 4 hour at different effector:target ratio. The mean percentage ± SD of specific lysis is indicated (n=3 per group). Data shown is representative of two independent experiments.