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. Author manuscript; available in PMC: 2010 Dec 22.
Published in final edited form as: Oncogene. 2009 Jun 1;28(31):2796–2805. doi: 10.1038/onc.2009.139

Figure 1. Strategy to characterize an anchorage-independent growth in vitro phenotype in combination with in vivo phenotypes.

Figure 1

To explore the relevance of the anchorage-independent phenotype for human cancer, we made use of a strategy to generate a signature for anchorage-independent growth capability from in vitro assays by a Bayesian probit regression model and then used the signature to assess the phenotype in a collection of human tumor samples.