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. Author manuscript; available in PMC: 2010 Dec 22.
Published in final edited form as: Oncogene. 2009 Jun 1;28(31):2796–2805. doi: 10.1038/onc.2009.139

Figure 5. Metastatic potential of lung cancer and melanoma is predicted by the anchorage-independent growth signature.

Figure 5

A. Prediction of metastasis of primary lung tumors by the gene signature for in vitro anchorage-independent growth ability. The predictions based on the anchorage-independent signature are shown for a lung tumor dataset that includes tumors with relapse but not with metastasis, and tumors with relapse and metastasis (GSE3593). Predicted probabilities are plotted for the groups with the defined outcome and statistically evaluated using Mann-Whitney U test. A bar indicates the mean value for each group.

B. Link with metastatic melanomas and anchorage-independent growth ability of breast cells (GSE8401). Predicted probabilities are plotted for the groups for primary and metastatic tumors, and statistically evaluated using Mann-Whitney U test. A bar indicates the mean value for each group.