Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ectopic expression of SNP1 accumulates Zn into lysosomes. Cells were transfected with pcDNA3.1-SNP1 to express HA-tagged SNP1. Confocal micrographs illustrate that colocalization (yellow) of FluoZin-3 (green) with the lysosomal marker Lysotracker (red) in the absence of chloroquine disphosphate (−CQ). Colocalization is eliminated in chloroquine disphosphate (+CQ)-treated SNP1-expressing cells, indicating lysosomes are a site of Zn accumulation in SNP1-expressing cells.
