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. Author manuscript; available in PMC: 2010 Dec 22.
Published in final edited form as: J Infect Dis. 2010 Jul 1;202(1):65–74. doi: 10.1086/653080

Fig 2. The clemizole-SCH503034 combination is synergistic across genotypes and in HCV-infected cells.

Fig 2

The antiviral effect of the clemizole-SCH503034 combination was determined using (A) genotype 1b luciferase reporter-linked replication assays, and (B) focus formation assays in cells infected with cell culture-grown HCV. Assays were performed following 72hr of treatment. Differential surface plot at the 95% confidence level are shown (generated using MacSynergyII). Peaks above the theoretical additive plane indicate synergy, whereas depressions below it indicate antagonism. The colors indicate the level of synergy/antagonism.