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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Mol Cancer Ther. 2010 Jul 27;9(8):2232–2242. doi: 10.1158/1535-7163.MCT-10-0336

Figure 4. Treatment with 17-DMAG results in the induction of apoptosis in K562 cells and K562/HS-5 co-cultures.

Figure 4

A. K562 cells were cultured in the presence or absence of HS-5 cells and exposed to indicated-concentrations of 17-DMAG for 48 hours. The percentage of apoptotic cells were assessed by Annexin V and PI staining, followed by flow cytometry. B. K562 cells were cultured in the presence or absence of HS-5 cells and treated with indicated concentrations of 17-DMAG for 8 hours. The resulting cell pellets were lysed and the expression of TrkA was assessed by immunoblotting. The levels of β-actin served as loading control.