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. 2010 Oct 13;48(12):4453–4458. doi: 10.1128/JCM.00953-10

TABLE 2.

Coreceptor assay resultsa

Patient no. MCT TROCAI
 Trofile Genotype PBVL
VL U87-X4 VL U87-R5 % X4 % R5 Categorization
1 + 0 9.28 × 106 0 100 R5 R5 R5 421,000
2 + 0 4.31 × 106 0 100 R5 R5 R5 7,350
3 + 0 1.27 × 104 0 100 R5 R5 R5 16,100
4 + 0 5.23 × 104 0 100 R5 R5 R5 28,000
5 + 0 5.68 × 106 0 100 R5 D/M R5 15,500
6 + 0 5.53 × 107 0 100 R5 ND NS 810
7 + 0 3.49 × 104 0 100 R5 ND R5 496
8 + 2.19 × 102 4.61 × 107 0 100 R5 R5 R5 114,000
9 + 4.38 × 102 1.00 × 109 0 100 R5 R5 NS 1,660
10 + 5.17 × 102 3.90 × 107 0 100 R5 R5 R5 10,500
11 + 6.87 × 102 2.53 × 107 0 100 R5 ND R5 835
12 + 7.06 × 102 7.19 × 108 0 100 R5 R5 R5 22,500
13 + 1.62 × 103 7.50 × 107 0 100 R5 R5 R5 47,000
14 + 1.99 × 103 6.41 × 107 0 100 R5 R5 R5 14,100
15 + 2.52 × 103 2.43 × 107 0.01 99.99 R5 ND R5 437
16 + 1.05 × 102 4.76 × 105 0.02 99.98 R5 R5 R5 50,900
17 + 9.40 × 102 1.89 × 106 0.05 99.95 R5 R5 R5 167,000
18 + 7.94 × 102 6.75 × 105 0.12 99.88 R5 R5 NA 6,060
19 + 1.55 × 103 3.75 × 105 0.41 99.59 R5 R5 R5 42,700
20 + ND ND ND ND NC ND R5 457
21 + ND ND ND ND NC ND NA 294
22 + ND ND ND ND NC ND NA 87
23 − 5.91 × 104 9.81 × 106 0.6 99.4 D/M D/M D/M 32,900
24 − 1.28 × 103 1.64 × 105 0.77 99.23 D/M ND D/M 827
25 − 2.70 × 107 1.11 × 109 2.37 97.63 D/M R5 D/M 40,000
26 − 7.47 × 105 2.75 × 107 2.65 97.35 D/M D/M D/M 192,000
27 − 2.21 × 105 2.89 × 106 7.1 92.9 D/M D/M R5 1,000,000
28 − 1.49 × 106 6.20 × 106 19.38 80.62 D/M D/M R5 74,300
29 − 7.98 × 106 1.84 × 106 81.26 18.74 D/M D/M R5 33,000
30 − 4.12 × 106 6.67 × 105 86.07 13.93 D/M D/M D/M 5,110
31 − 3.36 × 106 1.95 × 104 99.42 0.57 D/M ND NA 271
32 − 1.44 × 108 4.69 × 106 96.85 3.15 D/M D/M D/M 147,000
33 − 5.05 × 107 6.37 × 105 98.75 1.25 D/M D/M R5 306,000
a

VL U87-X4, viral load (number of HIV RNA copies/ml) in U87-CD4+CXCR4+ cell supernatant; VL U87-R5, viral load (number of HIV RNA copies/ml) in U87-CD4+CCR5+ cell supernatant; PBVL, plasma baseline viral load; NC, negative coculture; NS, no sample; ND, not determined (<1,000 HIV RNA copies/ml); NA, not amplifiable. Discordances between tropism predictions are shown in boldface.