TABLE 1.
HBV subgenotypes in relation to clinical features in patients with acute hepatitis B (n = 182)
| HBV subgenotype | No. of cases | % | Mean age (yr) ± SD | No. male | Mean HBV DNA (log IU/ml) ± SD | Mean TBIL (μmol/liter) ± SD | Mean PTA (%) ± SD | Mean ALT (IU/liter) ± SD | Mean AST (IU/liter) ± SD | % HBeAg+ |
|---|---|---|---|---|---|---|---|---|---|---|
| B1 | 2 | 1.10 | 40 ± 3 | 2 | 2.7 | 96.0 ± 46.7 | 117.1 ± 35.5 | 1,049 ± 969 | 203 ± 93 | 50 |
| B2 | 65 | 35.71 | 36 ± 12 | 54 | 4.0 ± 1.6 | 126.1 ± 96.5 | 95.2 ± 21.7 | 1,698 ± 1,000 | 885 ± 1188 | 24.6 |
| B3 | 1 | 0.55 | 30 | 1 | 3.7 | 24.4 | 30 | 1,388 | 327 | 0 |
| B4 | 1 | 0.55 | 25 | 1 | 4.4 | 107 | 97.4 | 3,181 | 2,787 | 0 |
| C1 | 2 | 1.10 | 34 ± 6 | 2 | 3.8 ± 1.6 | 67.1 ± 56.8 | 94.8 ± 105.6 | 2,393 ± 1,626 | 847 ± 44 | 50 |
| C2 | 110 | 60.44 | 37 ± 13 | 88 | 4.2 ± 1.4 | 135.1 ± 107.5 | 95.4 ± 233.1 | 1,661 ± 1,058 | 758 ± 680 | 37.2 |
| C3 | 1 | 0.55 | 18 | 1 | 6.7 | 233 | 30 | 890 | 890 | 0 |
| C4 | 0 | |||||||||
| D | 0 | |||||||||
| Pa | 0.56 | 0.45 | 0.44 | 0.47 | 0.67 | 0.74 | 0.46 | 0.09 |
a
The P values were obtained from comparison of parameters between HBV subgenotypes B2 and C2 and evaluated by multivariate analysis.