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. 2010 Sep 29;48(12):4363–4369. doi: 10.1128/JCM.01518-10

TABLE 6.

HBV subgenotypes in relation to disease progression

HBV subgenotype No. of patients witha:
AHB (n = 182) CHB (n = 3,247) LC (n = 613) ACLF (n = 55) HCC (n = 203)
B1 2 13 2 0 0
B2 65 463 69 6 12
B3 1 8 1 0 1
B4 1 12 1 1 0
C1 2 34 5 0 4
C2 110 2,653 520 48 183
C3 1 26 10 0 3
C4 0 7 0 0 0
D 0 31 5 0 0
C2 vs B2 1.7 5.7 7.5 8.0 15.3
a

AHB, acute hepatitis B; CHB, chronic hepatitis B; LC, liver cirrhosis; ACLF, acute-on-chronic liver failure; HCC, hepatocellular carcinoma.