TABLE 2.
Antifungal drug susceptibility profiles of C. bracarensisa
| Isolate (reference) | Source | MIC (μg/ml) of drug |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 5-FC | AMB | FLC | ITC | VRC | PSC | CASP | MICA | ANID | ||
| Clinical isolate 1 (this study) | Blood (Canada) | ≤0.06 | 0.25 | 8 | 0.25 | 0.12 | 0.5 | 0.06 | ≤0.008 | 0.03 |
| Clinical isolate 2 (this study) | Blood (Canada) | ≤0.06 | 0.5 | 8 | 0.25 | 0.12 | 0.5 | 0.06 | ≤0.008 | 0.03 |
| C. bracarensis TSa (3) | Vagina (Portugal) | 0.03 | 0.023 | 8 | 0.5 | 0.12 | 0.5 | 0.25 | ||
| Cagl-78 (3) | Stool (USA) | 0.12 | 1 | 8 | 0.25 | 0.06 | 0.5 | 0.25 | ||
| Cagl-112 (3) | Abscess (USA) | 0.12 | 0.094 | 4 | 0.25 | 0.06 | 0.25 | 0.25 | ||
| Cagl-121 (3) | Throat (USA) | 0.25 | 0.19 | 256 | >16 | 8 | >8 | 0.12 | ||
| C. bracarensis no. 1 (7) | Sputum (USA) | 8 | 16 | 0.03 | 0.015 | 0.06 | ||||
| C. bracarensis no. 2 (7) | Blood (USA) | 1 | 2 | 0.03 | 0.015 | 0.06 | ||||
a
C. bracarensis TS, C. bracarensis type strain NRRL Y-48270T (CBS10154); AMB, amphotericin B; FLC, fluconazole; ITC, itraconazole; VRC, voriconazole; PSC, posaconazole; CASP, caspofungin; MIC, micafungin; ANID, anidulafungin.