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. 2010 Oct 27;48(12):4474–4480. doi: 10.1128/JCM.00930-10

TABLE 2.

Prevalence of drug susceptibility to first-line anti-TB agents

Drug susceptibility Total (n = 185) No. (%)a of isolates grouped by history of TB treatment
Primary resistance (n = 144)b Acquired resistance (n = 41)c
Pansusceptibled 138 (74.6) 114 (79.2) 24 (58.5)
Non-MDRe 28 (15.1) 22 (15.3) 6 (14.6)
    INH 13 (7.0) 9 (6.3) 4 (9.8)
    SM 14 (7.6) 11 (7.6) 3 (7.3)
    RIF 2 (1.1) 2 (1.4) 0 (0.0)
    EMB 2 (1.1) 2 (1.4) 0 (0.0)
MDRf 19 (10.3) 8 (5.6) 11 (26.8)
a

The percentage in parentheses represents the number of isolates divided by the total number of isolates within each group.

b

Primary resistance was defined as the presence of drug susceptibility in isolates from TB patients who had never received any treatment for TB.

c

Acquired resistance was defined as the presence of drug susceptibility in isolates from TB patients who had a history of previous TB treatment.

d

Pansusceptibility was defined as sensitivity of isolates to all antibiotics.

e

Non-MDR TB was defined as resistance of isolates to at least one drug.

f

MDR TB was defined as resistance of isolates to both INH and RIF.