TABLE 1.
Induction ratios for ΔdosT and ΔdosS
| Gene no.a | Gene | Induction ratio |
Gene product | |
|---|---|---|---|---|
| ΔdosT strain | ΔdosS strain | |||
| DosR | ||||
| Rv0079 | 27.6 | 0.4 | Hypothetical protein | |
| Rv0080 | 12.5 | 1.2 | Conserved hypothetical protein | |
| Rv0081 | 3.1 | 1.0 | Probable transcriptional regulatory protein | |
| Rv0082 | 7.8 | 1.4 | Probable oxidoreductase | |
| Rv0569 | 14.9 | 0.8 | Conserved hypothetical protein | |
| Rv0570 | nrdZ | 5.9 | 0.5 | Probable ribonucleoside-diphosphate reductase |
| Rv0572c | 6.7 | 0.7 | Hypothetical protein | |
| Rv1733c | 5.8 | 0.7 | Probable conserved transmembrane protein | |
| Rv1736c | narX | 11.8 | 0.9 | Probable nitrate reductase |
| Rv1737c | narK2 | 18.6 | 0.5 | Possible nitrate/nitrite transporter |
| Rv1738 | 32.4 | 0.7 | Conserved hypothetical protein | |
| Rv1813c | 7.7 | 4.3 | Conserved hypothetical protein | |
| Rv1996 | 6.4 | 0.7 | Conserved hypothetical protein | |
| Rv2003c | 6.6 | 0.7 | Conserved hypothetical protein | |
| Rv2004c | 7.1 | 0.9 | Conserved hypothetical protein | |
| Rv2005c | 12.1 | 0.5 | Conserved hypothetical protein | |
| Rv2007c | fdxA | 82.0 | 0.9 | Probable ferredoxin |
| Rv2028c | 13.2 | 0.7 | Conserved hypothetical protein | |
| Rv2029c | pfkB | 20.8 | 0.9 | Probable phosphofructokinase |
| Rv2030c | 67.1 | 0.8 | Conserved hypothetical protein | |
| Rv2031c | hspX | 76.2 | 0.5 | 14-kD antigen, heat shock protein Hsp20 family |
| Rv2032 | acg | 30.8 | 0.5 | Conserved hypothetical protein |
| Rv2623 | 1.7 | 0.7 | Conserved hypothetical protein | |
| Rv2624c | 6.2 | 1.2 | Conserved hypothetical protein | |
| Rv2626c | 36.5 | 0.8 | Conserved hypothetical protein | |
| Rv2627c | 16.3 | 0.3 | Conserved hypothetical protein | |
| Rv2628 | 8.9 | 0.8 | Hypothetical protein | |
| Rv2629 | 8.1 | 0.9 | Conserved hypothetical protein | |
| Rv2630 | 4.2 | 1.6 | Hypothetical protein | |
| Rv3127 | 44.3 | 1.2 | Conserved hypothetical protein | |
| Rv3130c | tgs1 | 45.7 | 1.7 | Triacylglycerol synthase |
| Rv3131 | 41.0 | 0.9 | Conserved hypothetical protein | |
| Rv3132c | dosS | 16.7 | 0.4 | Sensor histidine kinase |
| Rv3133c | dosR | 11.1 | 0.6 | Two-component response regulator |
| Rv3134c | 26.0 | 0.7 | Conserved hypothetical protein | |
| Non-DosR | ||||
| Rv0467 | icl | 7.6 | 4.5 | Isocitrate lyase |
| Rv0791c | 5.0 | 3.5 | Conserved hypothetical protein | |
| Rv0792c | 4.4 | 3.2 | Probable GNTR family regulatory protein | |
| Rv0793 | 4.9 | 2.6 | Conserved hypothetical protein | |
| Rv2025c | 7.4 | 2.7 | Possible conserved membrane protein | |
| Rv2108 | PPE36 | 4.1 | 2.4 | PPE family protein |
| Rv2172c | 4.4 | 2.2 | Conserved hypothetical protein | |
| Rv3083 | 27.7 | 20.4 | Probable monooxygenase (hydroxylase) | |
| Rv3084 | lipR | 10.3 | 9.9 | Probable acetyl-hydrolase/esterase |
| Rv3086 | adhD | 7.3 | 8.8 | Probable zinc-type alcohol dehydrogenase |
| Rv3087 | 6.7 | 4.0 | Possible triacylglycerol synthase | |
| Rv3088 | 6.9 | 13.4 | Possible triacylglycerol synthase | |
| Rv3089 | fadD13 | 7.1 | 4.3 | Probable fatty-acid coenzyme A (CoA) ligase |
| Rv3841 | bfrB | 17.7 | 15.3 | Possible bacterioferritin |
a
Genes in the ΔdosT strain that were included in the table had an induction ratio of at least 4-fold and a corresponding SAM q value of 0.