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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Front Neuroendocrinol. 2010 Jul 30;32(1):43–52. doi: 10.1016/j.yfrne.2010.07.005

Figure 2.

Figure 2

Crosstalk between membrane receptors targeting of olfactory nerves and migration of GnRH neurons. HGF/Met, chemokine and Semaphorin pathways have been implicated in both olfactory nerve targeting and GnRH neuron migration. SDF-1 (CXCL12) chemokine and its receptor CXCR4 may interact with HGF (hepatocyte growth factor)/cMET which in turn may interact with semaphorins and their plexin receptors in the absence or presence of docking intermediates NP2 (neuropilin 2).