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. Author manuscript; available in PMC: 2010 Dec 22.
Published in final edited form as: Bull Math Biol. 2009 Dec 16;72(3):611–644. doi: 10.1007/s11538-009-9463-1

Fig. 1.

Fig. 1

The cell division-based program. (1) Immature APCs pick up antigen at the site of infection at a time-dependent rate a(t). These APCs mature and migrate to the lymph node. (2) Mature antigen-bearing APCs present antigen to naïve T cells causing them to activate and enter the minimal developmental program of m divisions. (3) Activated T cells that have completed the minimal program continue to divide upon further interaction with mature APCs for up to n additional divisions. (4) T cells that have completed the maximal number of divisions stop dividing and wait for apoptosis. Although not indicated, each cell in the diagram has a natural death rate according to its kind.