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. Author manuscript; available in PMC: 2010 Dec 22.
Published in final edited form as: Bull Math Biol. 2009 Dec 16;72(3):611–644. doi: 10.1007/s11538-009-9463-1

Table 1.

Cell division-based model’s parameters. Concentrations are in units of k/μL, and time is measured in days

Parameter Description Estimate
A0(0) Initial concentration of immature APCs sA/d0 = 10
T0(0) Initial concentration of naïve T cells sT/δ0 = 0.04
sA Supply rate of immature APCs 0.3
sT Supply rate of naïve T cells 0.0012
d0 Death/turnover rate of immature APCs 0.03
δ0 Death/turnover rate of naïve T cells 0.03
d1 Death/turnover rate of mature APCs 0.8
δ1 Death/turnover rate of effector T cells 0.4
k Kinetic coefficient 20
m Number of divisions in minimal developmental program 7
n Maximum number of antigen-dependent divisions 3, 10, 16
ρ Duration of one T cell division 1/3
σ Duration of minimal developmental program 3
a(t) Rate of APC stimulation c1[0,b] or (3)
b Duration of antigen availability 10
c Level of APC stimulation 1